General Lab Resources
- Formal Report Guidelines (html) | (.pdf)
- Multi-Step Synthesis of Benzilic Acid (.pdf)
- MOPAC 7 Manual (.pdf)
Links to Watch Lab Experiment Recordings
- Synthesis of Triphenylmethanol by Grignard Reaction, February 2, 2021
In this video experiment we look at the synthesis of triphenylmenthanol via a Grignard reaction. Bromobenzene is first reacted with magnesium metal to make phenyl magnesium bromide. Benzophenone is then added to the Grignard reagent in situ to form the triphenylmethanol. The Grignard video experiment is being broken into four videos that span setting up the apparatus, conducting the reaction, isolating the product, and characterization of the product. The data for this lab should be taken in your laboratory notebook from the videos.
- Grignard Reaction Part 1: Apparatus. This video is 22 minutes in length. Watch Locally | Watch YouTube
- Grignard Reaction Part 2: Reaction. This video is 33 minutes in length. Watch Locally | Watch YouTube
- Grignard Reaction Part 3: Isolation. This video is 44 minutes in length. Watch Locally | Watch YouTube
- Grignard Reaction Part 4: Characterization. This video is 22 minutes in length. Watch Locally | Watch YouTube
- Multistep Synthesis of Benzilic Acid, February 18, 2021
The Multistep Synthesis of Benzilic Acid is actually three individual experiments. In the first stage we react benzaldehyde with thiamine hydrochloride to produce benzoin. In state two benzoin is oxidized to benzil. Stage three reacts benzil in a base catalyzed isomerization reaction to afford benzilic acid. Each of the three labs will be broken into individual video segments of reaction, isolation, and characterization. These three experiments will be combined into a single formal report on the synthesis of benzilic acid.
Step 1 - Synthesis of benzoin from benzaldehyde
Step 2 - Oxidation of benzoin to form benzil
Step 3 - Base catalyzed isomerization of benzil to form benzilic acid